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Recent studies have reported that two drugs, MRTX1133 and BI-KRASG12D1-3, are able to selectively inhibit the viability of KRAS mutant tumour cells in clinical trials [123]

In addition to self-reported smoking status and CO measures taken at each visit, urinary anabasine and anatabine concentration will be used as the principle objective measure of the primary outcome (continuous abstinence from smoking during the last 4 weeks of treatment)

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The proposed introduction date for the new warnings was also put back several months