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The consequences of this repeated and prolonged episodes of reflux can damage the inner lining of the esophagus and increases the risk of esophageal cancer Tobacco and Peptic Ulcer Smoking stimulates acid secretion from stomach and attenuates the defense mechanisms like decrease in blood flow, mucus and bicarbonate production

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Scientists studied adult mice that were susceptible (A/J strain) or resistant (C3H strain) to lung tumors and were exposed to the tobacco carcinogen NNK (Razani-Boroujerdi and Sopori 2007)

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